Research

Fragment-based drug discovery on protein-protein interactions to make chemical probes and identify new therapeutic principles

Bioinorganic chemistry, structure/function of redox active enzymes, reactive oxygen species, labelled proteins/peptides/DNA/RNA

Targeted medicinal chemistry towards antibiotics and anti-cancer compounds with focus on compounds aiming to overcome drug-resistance

Artificial enzymes, cyclodextrin chemistry and nitrogen containing drugs

We work to discover novel tool compounds for CNS disorders as well as develop new synthetic methodology relevant to medicinal chemistry.

Developing biocompatible fluorescent nanomaterials, methods, and instruments for advanced biomedical imaging

Dendrimers in medicine and new antibiotics

Development of tool compounds for CNS disorders

Structural biology - protein-ligand interactions

Medicinal chemistry with focus on engineered ligands for GABA and GHB targets

Structural biology

Understanding the interplay between disruptions in lipid homeostasis and Parkinson's Disease using cell biology and biophysics

Protein structures and protein-protein interactions. Protein formulation. X-ray crystallography and SAXS.

Biophysical and single particle studies on biomolcules that control abberant biological function

Bioinorganic chemistry and spectroscopy, Protein structure and function

Radiopharmaceutical Chemistry - From CNS to cancer

Manufacturing and clinical use of PET radiopharmaceuticals

Computational chemistry and AI/ML for drug discovery and prediction of reaction outcomes

Medicinal chemistry with a focus on peptides, proteins and carbohydrates. Disease areas include diabtes, obesity, and some cancers

Medicinal chemistry aiming at CNS-active therapeutics

Application of computational methods/molecular modelling in drug research

Receptor structural biology

Design and synthesis of fluoresent dyes and probes, fluorescent nanoparticles, steady-state and time-resolved fluorescence spectroscopy

Organic synthesis and catalysis

Structural biology - lysogeny switches of bacteriophages implicated in gene transfer between pathogens

Investigation of GPCR signaling oathways using fluorescence imaging and customized cellular assays

Chemical biology based on organic-, polymer- and computational chemistry within enzymology, recognition and catalysis

Organic and supramolecular chemistry

With a foundation in chemical synthesis, we explore the function of small molecules, peptides, and proteins in biology

Organic chemistry with the focus on carbohydrates, biomass conversion, medicinal chemistry.

Molecular and molecule-based magnetic materials

Organic and supramolecular chemisty

Discovery of drug-like cyclic peptides

Computational chemistry: NMR and ESR spectra, reaction mechanisms, radiation damage to biomolecules

Nanoscale investigation of GPCRs and transporters.

Targetting receptor complexes with therapeutic peptides

Sustainable bioactive natural products-based drug discovery and development of advanced bioanalytical NMR/MS technologies

Bioinorganic chemistry of natural and chemically modified peptides, proteins and oligonucleotides

Synthesis and design of permeation enhancers for oral delivery of biopharmaceutical drugs

Development of tool compounds for studying GPCRs in vitro and in vivo and fluorescent tracers for assay development

Medicinal chemistry with focus on metabolic diseases, GPCRs and lipid mediators

Molecular pharmacology of drug targets (GABA receptors, CaMKII, SLC6 transporters)

Development of new emissive materials for bio-imaging with a focus on the NIR I and NIR II region